Modern-day Termez bears few traces of its colourful cosmopolitan history. However, there are a lot of ancient monuments and sites attesting to more glorious times.Old Termez, the original, pre-Mongol city is 6 km northwest of the modern city.The Hakkim at Termezi Mausoleum (10th century), Mosque (12th century) and Timurid Khonako (15th century) grew up around the name of the saint patron of Termez, Sufi Abu Abdullah Mohammed-ibn-Ali-al-Termezi, nicknamed "al-Hakkim" (the wise). He was a ninth-century Sufi, jurist, mystic, philosopher and poet.The Sultan Saodat Complex was known as a family necropolis of Termez Sayyids – the descendants of the prophet Mohammed. It was founded by Sayyid Hasan al Emir in the 9th century and grew till the 15th. The Buddhist monastery complex of Kara Tepe is unique in Central Asia, a rock-hewn Buddhist cave complex. But it is not always available because an access there necessitating an official permission. The Fayaz Tepe Site consists of the archaeological remains of the 2nd century Buddhist temple and a monastery complex. The monastery was destroyed in the 5th century by Sassanids troops and later it was used as a burial ground. Djarkurgan Minaret (22 m) is 35 km from Termez in a small town of Djarkurgan.It is another monument of Karakhanid architecture and was erected in 1108. The trunk of minaret consists of 16 semicolumns laid of herringbone brickwork with band of Koranic inscription in Kufic style which suggests that the minaret was double linked and had 50 meters height. The History museum has a good collection of artifacts excavated from local archaeological sites.

Bridge of Friendship was the main entry point for Soviet troops into Afghanistan in 1979. It was built across the Amudarya, which is a natural border between two countries.